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Le glutathion, en tant que principal tampon redox intracellulaire, se retrouve en premire ligne de cette dfense : plusieurs tudes ont montr que les niveaux de GSH hpatique sont significativement rduits chez les patients atteints de NAFLD avance, ce qui traduit un puisement des dfenses antioxydantes face la surcharge lipidique

However, factors such as aging, poor diet, stress, and environmental toxins can deplete glutathione levels, leading to oxidative stress and accelerated aging